Ontology highlight
ABSTRACT:
SUBMITTER: Kovaleva KS
PROVIDER: S-EPMC6335999 | biostudies-literature | 2018 Dec
REPOSITORIES: biostudies-literature
Kovaleva Kseniya S KS Zubkov Fedor I FI Bormotov Nikolay I NI Novikov Roman A RA Dorovatovskii Pavel V PV Khrustalev Victor N VN Gatilov Yuriy V YV Zarubaev Vladimir V VV Zarubaev Vladimir V VV Yarovaya Olga I OI Shishkina Larisa N LN Salakhutdinov Nariman F NF
MedChemComm 20181026 12
The design and synthesis of a series of novel d-(+)-camphor <i>N</i>-acylhydrazones exhibiting inhibitory activity against vaccinia and influenza viruses are presented. An easy pathway to camphor-based <i>N</i>-acylhydrazones containing in their structure aliphatic, aromatic, and heterocyclic pharmacophore scaffolds has been developed. The conformation and configuration of the synthesized hydrazones were thoroughly characterized by a complete set of spectral characterization techniques, includin ...[more]