Ontology highlight
ABSTRACT:
SUBMITTER: Pollack S
PROVIDER: S-EPMC6341299 | biostudies-literature | 2019 Feb
REPOSITORIES: biostudies-literature
Pollack Samuela S Igo Robert P RP Jensen Richard A RA Christiansen Mark M Li Xiaohui X Cheng Ching-Yu CY Ng Maggie C Y MCY Smith Albert V AV Rossin Elizabeth J EJ Segrè Ayellet V AV Davoudi Samaneh S Tan Gavin S GS Chen Yii-Der Ida YI Kuo Jane Z JZ Dimitrov Latchezar M LM Stanwyck Lynn K LK Meng Weihua W Hosseini S Mohsen SM Hosseini S Mohsen SM Imamura Minako M Nousome Darryl D Kim Jihye J Hai Yang Y Jia Yucheng Y Ahn Jeeyun J Leong Aaron A Shah Kaanan K Park Kyu Hyung KH Guo Xiuqing X Ipp Eli E Taylor Kent D KD Adler Sharon G SG Sedor John R JR Freedman Barry I BI Lee I-Te IT Sheu Wayne H-H WH Kubo Michiaki M Takahashi Atsushi A Hadjadj Samy S Marre Michel M Tregouet David-Alexandre DA Mckean-Cowdin Roberta R Varma Rohit R McCarthy Mark I MI Groop Leif L Ahlqvist Emma E Lyssenko Valeriya V Agardh Elisabet E Morris Andrew A Doney Alex S F ASF Colhoun Helen M HM Toppila Iiro I Sandholm Niina N Groop Per-Henrik PH Maeda Shiro S Hanis Craig L CL Penman Alan A Chen Ching J CJ Hancock Heather H Mitchell Paul P Craig Jamie E JE Chew Emily Y EY Paterson Andrew D AD Grassi Michael A MA Palmer Colin C Bowden Donald W DW Yaspan Brian L BL Siscovick David D Cotch Mary Frances MF Wang Jie Jin JJ Burdon Kathryn P KP Wong Tien Y TY Klein Barbara E K BEK Klein Ronald R Rotter Jerome I JI Iyengar Sudha K SK Price Alkes L AL Sobrin Lucia L
Diabetes 20181128 2
To identify genetic variants associated with diabetic retinopathy (DR), we performed a large multiethnic genome-wide association study. Discovery included eight European cohorts (<i>n</i> = 3,246) and seven African American cohorts (<i>n</i> = 2,611). We meta-analyzed across cohorts using inverse-variance weighting, with and without liability threshold modeling of glycemic control and duration of diabetes. Variants with a <i>P</i> value <1 × 10<sup>-5</sup> were investigated in replication cohor ...[more]