Role of IL-17RA in the proliferative priming of hepatocytes in liver regeneration.
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ABSTRACT:
SUBMITTER: Piobbico D
PROVIDER: S-EPMC6342078 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Publications
Role of IL-17RA in the proliferative priming of hepatocytes in liver regeneration.
Piobbico Danilo D Bartoli Daniela D Pieroni Stefania S De Luca Antonella A Castelli Marilena M Romani Luigina L Servillo Giuseppe G Della-Fazia Maria Agnese MA
Cell cycle (Georgetown, Tex.) 20181111 21-22
A tight link has been established between inflammation and cancer. Liver regeneration is a widely used model to study the correlation between inflammation and proliferation. IL-6 is essentially involved in liver regeneration and in cancer. Recently, IL-17A has been shown to regulate not only inflammation, but also cell proliferation. Here, we analyze the role played by IL-17A signaling in liver regeneration by comparing cell proliferation in Wild Type and IL-17RA<sup>-/-</sup> mice. Partial hepa ...[more]
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