Ontology highlight
ABSTRACT:
SUBMITTER: Weigelt CM
PROVIDER: S-EPMC6343102 | biostudies-literature | 2019 Feb
REPOSITORIES: biostudies-literature
Weigelt Carina M CM Hahn Oliver O Arlt Katharina K Gruhn Matthias M Jahn Annika J AJ Eßer Jacqueline J Werner Jennifer A JA Klein Corinna C Büschges Ansgar A Grönke Sebastian S Partridge Linda L
Life science alliance 20190122 1
miRNAs are small, non-coding RNAs that regulate gene expression post-transcriptionally. We used small RNA sequencing to identify tissue-specific miRNAs in the adult brain, thorax, gut, and fat body of <i>Drosophila melanogaster</i> One of the most brain-specific miRNAs that we identified was miR-210, an evolutionarily highly conserved miRNA implicated in the regulation of hypoxia in mammals. In <i>Drosophila</i>, we show that miR-210 is specifically expressed in sensory organs, including photore ...[more]