Ontology highlight
ABSTRACT:
SUBMITTER: Casan JML
PROVIDER: S-EPMC6343614 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Casan J M L JML Wong J J Northcott M J MJ Opat S S
Human vaccines & immunotherapeutics 20180906 12
Since the inception of rituximab in the 1990s, anti-CD20 monoclonal antibodies have revolutionised the treatment of B cell hematological malignancies and have become a cornerstone of modern gold-standard practice. Additionally, the potent efficacy of these agents in depleting the B cell compartment has been used in the management of a broad array of autoimmune diseases. Multiple iterations of these agents have been investigated and are routinely used in clinical practice. In this review, we will ...[more]