Ontology highlight
ABSTRACT:
SUBMITTER: Garcia D
PROVIDER: S-EPMC6344045 | biostudies-literature | 2019 Jan
REPOSITORIES: biostudies-literature
Cell reports 20190101 1
The AMP-activated protein kinase (AMPK) is a highly conserved master regulator of metabolism, whose activation has been proposed to be therapeutically beneficial for the treatment of several metabolic diseases, including nonalcoholic fatty liver disease (NAFLD). NAFLD, characterized by excessive accumulation of hepatic lipids, is the most common chronic liver disease and a major risk factor for development of nonalcoholic steatohepatitis, type 2 diabetes, and other metabolic conditions. To asses ...[more]