Ontology highlight
ABSTRACT:
SUBMITTER: Offley SR
PROVIDER: S-EPMC6344269 | biostudies-literature | 2019 Feb
REPOSITORIES: biostudies-literature
Offley Sarah R SR Schmidt Martin C MC
Current genetics 20180917 1
The phosphorylation status of a protein is highly regulated and is determined by the opposing activities of protein kinases and protein phosphatases within the cell. While much is known about the protein kinases found in Saccharomyces cerevisiae, the protein phosphatases are much less characterized. Of the 127 protein kinases in yeast, over 90% are in the same evolutionary lineage. In contrast, protein phosphatases are fewer in number (only 43 have been identified in yeast) and comprise multiple ...[more]