Ontology highlight
ABSTRACT:
SUBMITTER: Di Venanzio G
PROVIDER: S-EPMC6347727 | biostudies-literature | 2019 Jan
REPOSITORIES: biostudies-literature
Di Venanzio Gisela G Moon Ki Hwan KH Weber Brent S BS Lopez Juvenal J Ly Pek Man PM Potter Robert F RF Dantas Gautam G Feldman Mario F MF
Proceedings of the National Academy of Sciences of the United States of America 20190109 4
<i>Acinetobacter baumannii</i> (<i>Ab</i>) is a nosocomial pathogen with one of the highest rates of multidrug resistance (MDR). This is partially due to transmissible plasmids. Many <i>Ab</i> strains harbor a constitutively active type VI secretion system (T6SS) that is employed to kill nonkin bacteria. T6SS and plasmid conjugation both involve cell-to-cell contact. Paradoxically, successful conjugation requires the survival of the recipient, which is the target of the T6SS. Thus, an active T6S ...[more]