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MiR-124, a potential therapeutic target in colorectal cancer.


ABSTRACT: Recently, miR-124 has been regarded as a critical modulator of colorectal cancer. We here summarize the studies on the role and mechanism of miR-124 in colorectal cancer. They indicate that miR-124 is methylated during carcinogenesis and functions as a tumor-suppressor in colorectal cancer. miR-124 might serve as a potential diagnostic biomarker and therapeutic target in colorectal cancer in the foreseeable future.

SUBMITTER: Qin Z 

PROVIDER: S-EPMC6348970 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature

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miR-124, a potential therapeutic target in colorectal cancer.

Qin Zhen Z   Liu Xia X  

OncoTargets and therapy 20190122


Recently, miR-124 has been regarded as a critical modulator of colorectal cancer. We here summarize the studies on the role and mechanism of miR-124 in colorectal cancer. They indicate that miR-124 is methylated during carcinogenesis and functions as a tumor-suppressor in colorectal cancer. miR-124 might serve as a potential diagnostic biomarker and therapeutic target in colorectal cancer in the foreseeable future. ...[more]

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