Ontology highlight
ABSTRACT:
SUBMITTER: Wu N
PROVIDER: S-EPMC6349181 | biostudies-literature | 2019 Feb
REPOSITORIES: biostudies-literature
Wu Nan N Jiang Mingzuo M Han Yuying Y Liu Haiming H Chu Yi Y Liu Hao H Cao Jiayi J Hou Qiuqiu Q Zhao Yu Y Xu Bing B Xie Xin X
Journal of cellular and molecular medicine 20181128 2
The RNA helicase p68 (DDX5), a key player in RNA metabolism, belongs to the DEAD box family and is involved in the development of colorectal cancer. Here, we found both DDX5 and O-GlcNAcylation are up-regulated in colorectal cancer. In addition, DDX5 protein level is significantly positively correlated with the expression of O-GlcNAcylation. Although it was known DDX5 protein could be regulated by post-translational modification (PTM), how O-GlcNAcylation modification regulated of DDX5 remains u ...[more]