Ontology highlight
ABSTRACT:
SUBMITTER: Bonora M
PROVIDER: S-EPMC6349394 | biostudies-literature | 2019 Jan
REPOSITORIES: biostudies-literature
Nature reviews. Cardiology 20190101 1
A large body of evidence indicates that mitochondrial dysfunction has a major role in the pathogenesis of multiple cardiovascular disorders. Over the past 2 decades, extraordinary efforts have been focused on the development of agents that specifically target mitochondria for the treatment of cardiovascular disease. Despite such an intensive wave of investigation, no drugs specifically conceived to modulate mitochondrial functions are currently available for the clinical management of cardiovasc ...[more]