Ontology highlight
ABSTRACT:
SUBMITTER: Santos-Vizcaino E
PROVIDER: S-EPMC6351221 | biostudies-literature | 2019 Apr
REPOSITORIES: biostudies-literature
Santos-Vizcaino Edorta E Haley Henry H Gonzalez-Pujana Ainhoa A Orive Gorka G Hernandez Rosa Maria RM Luker Gary D GD Pedraz Jose Luis JL
Journal of biophotonics 20180925 4
Imaging of implanted hydrogel-based biosystems usually requires indirect labeling of the vehicle or cargo, adding complexity and potential risk of altering functionality. Here, for the first time, it is reported that incorporation of genipin into the design of immunoisolation devices can be harnessed for in vivo imaging. Using cell-compatible in situ cross-linking reactions, a fast, efficient and noncytotoxic procedure is shown to maximize fluorescence of microcapsules. Moreover, genipin is vali ...[more]