SLIME: robust, high-speed 3D microvascular mapping.
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ABSTRACT:
SUBMITTER: Liu Y
PROVIDER: S-EPMC6351571 | biostudies-literature | 2019 Jan
REPOSITORIES: biostudies-literature
Publications
SLIME: robust, high-speed 3D microvascular mapping.
Liu Yehe Y Broberg Meredith C G MCG Watanabe Michiko M Rollins Andrew M AM Jenkins Michael W MW
Scientific reports 20190129 1
Three dimensional (3D) microvascular imaging of cubic millimeter to centimeter size volumes often requires much time and expensive instruments. By combining optical clearing with a novel scatter-based optical coherence tomography (OCT) contrast agent, we have greatly extended OCT imaging depth in excised tissues while maintaining a simple and low cost approach that does not require in-depth OCT knowledge. The new method enables fast 3D microvascular mapping in large tissue volumes, providing a p ...[more]
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