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Corneal re-innervation following refractive surgery treatments.


ABSTRACT: Laser refractive surgery is one of the most performed surgical procedures in the world. Although regarded safe and efficient, it has side effects. All of the laser based refractive surgical procedures invoke corneal nerve injury to some degree. The impact of this denervation can range from mild discomfort to neurotrophic corneas. Currently, three techniques are widely used for laser vision correction: small incision lenticule extraction, laser-assisted keratomileusis in situ and photorefractive keratotomy. Each of these techniques affects corneal innervation differently and has a different pattern of nerve regeneration. The purpose of this review is to summarize the different underlying mechanisms for corneal nerve injury and compare the different patterns of corneal reinnervation.

SUBMITTER: Bandeira F 

PROVIDER: S-EPMC6352585 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature

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Corneal re-innervation following refractive surgery treatments.

Bandeira Francisco F   Yusoff Nur Zahira NZ   Yam Gary Hin-Fai GH   Mehta Jodhbir Singh JS  

Neural regeneration research 20190401 4


Laser refractive surgery is one of the most performed surgical procedures in the world. Although regarded safe and efficient, it has side effects. All of the laser based refractive surgical procedures invoke corneal nerve injury to some degree. The impact of this denervation can range from mild discomfort to neurotrophic corneas. Currently, three techniques are widely used for laser vision correction: small incision lenticule extraction, laser-assisted keratomileusis in situ and photorefractive  ...[more]

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