Ontology highlight
ABSTRACT:
SUBMITTER: Schlosser J
PROVIDER: S-EPMC6356764 | biostudies-literature | 2018 Dec
REPOSITORIES: biostudies-literature
Schlosser Josephine J Dähnert Lisa L Dremsek Paul P Tauscher Kerstin K Fast Christine C Ziegler Ute U Gröner Albrecht A Ulrich Rainer G RG Groschup Martin H MH Eiden Martin M
Viruses 20181220 1
Hepatitis E virus (HEV) is the causative agent of acute hepatitis E in humans in developing countries, but autochthonous cases of zoonotic genotype 3 (HEV-3) infection also occur in industrialized countries. In contrast to swine, rats, and rabbits, natural HEV infections in mice have not yet been demonstrated. The pig represents a well-established large animal model for HEV-3 infection, but a suitable small animal model mimicking natural HEV-3 infection is currently missing. Therefore, we experi ...[more]