Emerging Role of Vitamins D and K in Modulating Uremic Vascular Calcification: The Aspect of Passive Calcification.
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SUBMITTER: Hou YC
PROVIDER: S-EPMC6356797 | biostudies-literature | 2019 Jan
REPOSITORIES: biostudies-literature
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Emerging Role of Vitamins D and K in Modulating Uremic Vascular Calcification: The Aspect of Passive Calcification.
Hou Yi-Chou YC Lu Chien-Lin CL Zheng Cai-Mei CM Chen Ruei-Ming RM Lin Yuh-Feng YF Liu Wen-Chih WC Yen Tzung-Hai TH Chen Remy R Lu Kuo-Cheng KC
Nutrients 20190112 1
Vascular calcification is a critical complication in patients with chronic kidney disease (CKD) because it is predictive of cardiovascular events and mortality. In addition to the traditional mechanisms associated with endothelial dysfunction and the osteoblastic transformation of vascular smooth muscle cells (VSMCs), the regulation of calcification inhibitors, such as calciprotein particles (CPPs) and matrix vesicles plays a vital role in uremic vascular calcification in CKD patients because of ...[more]
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