Ontology highlight
ABSTRACT:
SUBMITTER: Hilton NA
PROVIDER: S-EPMC6359937 | biostudies-literature | 2018 Aug
REPOSITORIES: biostudies-literature
Hilton Nicholas A NA Sladewski Thomas E TE Perry Jenna A JA Pataki Zemplen Z Sinclair-Davis Amy N AN Muniz Richard S RS Tran Holly L HL Wurster Jenna I JI Seo Jiwon J de Graffenried Christopher L CL
Molecular microbiology 20180725 3
The protist parasite Trypanosoma brucei is an obligate extracellular pathogen that retains its highly polarized morphology during cell division and has evolved a novel cytokinetic process independent of non-muscle myosin II. The polo-like kinase homolog TbPLK is essential for transmission of cell polarity during division and for cytokinesis. We previously identified a putative TbPLK substrate named Tip of the Extending FAZ 1 (TOEFAZ1) as an essential kinetoplastid-specific component of the T. br ...[more]