A distinctive DNA methylation pattern in insufficient sleep.
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ABSTRACT:
SUBMITTER: Lahtinen A
PROVIDER: S-EPMC6362278 | biostudies-literature | 2019 Feb
REPOSITORIES: biostudies-literature
Publications
A distinctive DNA methylation pattern in insufficient sleep.
Lahtinen Alexandra A Puttonen Sampsa S Vanttola Päivi P Viitasalo Katriina K Sulkava Sonja S Pervjakova Natalia N Joensuu Anni A Salo Perttu P Toivola Auli A Härmä Mikko M Milani Lili L Perola Markus M Paunio Tiina T
Scientific reports 20190204 1
Short sleep duration or insomnia may lead to an increased risk of various psychiatric and cardio-metabolic conditions. Since DNA methylation plays a critical role in the regulation of gene expression, studies of differentially methylated positions (DMPs) might be valuable for understanding the mechanisms underlying insomnia. We performed a cross-sectional genome-wide analysis of DNA methylation in relation to self-reported insufficient sleep in individuals from a community-based sample (79 men, ...[more]
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