Ontology highlight
ABSTRACT:
SUBMITTER: Brzuzan P
PROVIDER: S-EPMC6362533 | biostudies-literature | 2019 Jan
REPOSITORIES: biostudies-literature
Brzuzan Paweł P Woźny Maciej M Lewczuk Bogdan B Florczyk Maciej M Gomułka Piotr P Budzińska Paulina P Wesołowski Michał M Dobosz Stefan S
Experimental biology and medicine (Maywood, N.J.) 20190121 1
<h4>Impact statement</h4>The delivery of short snippets of RNA, such as synthetic miRNA agents, is an essential step for achieving RNA-mediated knockdown, which has not been studied in sufficient detail in fish. Our results indicate that a MiR92b-3p mimic may be effectively delivered via intraperitoneal injection to the spleen and the liver of whitefish, and that it likely achieves functionality without causing any apparent toxic effects in the challenged animals. We report the novel finding tha ...[more]