LncRNAs join hands together to regulate neuroblastoma progression.
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ABSTRACT:
SUBMITTER: Mondal T
PROVIDER: S-EPMC6370385 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Publications
LncRNAs join hands together to regulate neuroblastoma progression.
Mondal Tanmoy T Kanduri Chandrasekhar C
Molecular & cellular oncology 20181217 1
Trait associated single nucleotide polymorphisms often overlap with noncoding transcripts but their contribution to disease phenotype is poorly investigated. Our study on neuroblastoma risk associated 6p22.3 locus derived long noncoding RNAs (lncRNAs) demonstrates that functional co-operation between sense-antisense <i>CASC15</i> and <i>NBAT1</i> lncRNAs control neuroblastoma progression via regulating <i>SOX9-CHD7-USP36</i> regulatory axis. ...[more]
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