Ontology highlight
ABSTRACT:
SUBMITTER: Bender J
PROVIDER: S-EPMC6371745 | biostudies-literature | 2019 Feb
REPOSITORIES: biostudies-literature
Bender Jonathan J Anderson Bailey B Bloom David A DA Rabah Raja R McDougall Rhonda R Vats Pankaj P Mody Rajen R
Cold Spring Harbor molecular case studies 20190201 1
Infantile fibrosarcoma (IFS) is a rare soft-tissue sarcoma, which classically presents as an aggressive and rapidly enlarging tumor over the distal extremities of children in their first year of life. The presence of <i>ETV6</i> and <i>NTRK3</i> gene rearrangement is characteristic of IFS, which can be detected on routine fluorescence in situ hybridization (FISH) testing. Patients with IFS typically respond well to surgical resection and chemotherapy and have an overall survival of ∼90%. In this ...[more]