Ontology highlight
ABSTRACT:
SUBMITTER: Steinmark IE
PROVIDER: S-EPMC6375549 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Steinmark Ida Emilie IE James Arjuna L AL Chung Pei-Hua PH Morton Penny E PE Parsons Maddy M Dreiss Cécile A CA Lorenz Christian D CD Yahioglu Gokhan G Suhling Klaus K
PloS one 20190214 2
The only way to visually observe cellular viscosity, which can greatly influence biological reactions and has been linked to several human diseases, is through viscosity imaging. Imaging cellular viscosity has allowed the mapping of viscosity in cells, and the next frontier is targeted viscosity imaging of organelles and their microenvironments. Here we present a fluorescent molecular rotor/FLIM framework to image both organellar viscosity and membrane fluidity, using a combination of chemical t ...[more]