Ontology highlight
ABSTRACT:
SUBMITTER: Rubalskii E
PROVIDER: S-EPMC6376040 | biostudies-literature | 2019 Feb
REPOSITORIES: biostudies-literature
Scientific reports 20190214 1
Fibrin glue has been used clinically for decades in a wide variety of surgical specialties and is now being investigated as a medium for local, prolonged drug delivery. Effective local delivery of antibacterial substances is important perioperatively in patients with implanted medical devices or postoperatively for deep wounds. However, prolonged local application of antibiotics is often not possible or simply inadequate. Biofilm formation and antibiotic resistance are also major obstacles to an ...[more]