Combined transcriptome and proteome profiling reveals specific molecular brain signatures for sex, maturation and circalunar clock phase.
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ABSTRACT:
SUBMITTER: Schenk S
PROVIDER: S-EPMC6377233 | biostudies-literature | 2019 Feb
REPOSITORIES: biostudies-literature
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Combined transcriptome and proteome profiling reveals specific molecular brain signatures for sex, maturation and circalunar clock phase.
Schenk Sven S Bannister Stephanie C SC Sedlazeck Fritz J FJ Anrather Dorothea D Minh Bui Quang BQ Bileck Andrea A Hartl Markus M von Haeseler Arndt A Gerner Christopher C Raible Florian F Tessmar-Raible Kristin K
eLife 20190215
Many marine animals, ranging from corals to fishes, synchronise reproduction to lunar cycles. In the annelid <i>Platynereis dumerilii,</i> this timing is orchestrated by an endogenous monthly (circalunar) clock entrained by moonlight. Whereas daily (circadian) clocks cause extensive transcriptomic and proteomic changes, the quality and quantity of regulations by circalunar clocks have remained largely elusive. By establishing a combined transcriptomic and proteomic profiling approach, we provide ...[more]
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