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Sequencing of anthracyclines and taxanes in neoadjuvant and adjuvant therapy for early breast cancer.


ABSTRACT:

SUBMITTER: Zaheed M 

PROVIDER: S-EPMC6378927 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature

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Sequencing of anthracyclines and taxanes in neoadjuvant and adjuvant therapy for early breast cancer.

Zaheed Milita M   Wilcken Nicholas N   Willson Melina L ML   O'Connell Dianne L DL   Goodwin Annabel A  

The Cochrane database of systematic reviews 20190218


<h4>Background</h4>Anthracyclines and taxanes are chemotherapeutic agents widely used in a sequential regimen in the adjuvant and neoadjuvant treatment of early breast cancer to reduce the risk of cancer recurrence. Standard practice is to administer anthracycline-based chemotherapy followed by a taxane. Anthracyclines tend to be administered first as they were established before taxanes for treatment of early breast cancer.<h4>Objectives</h4>To assess whether the sequence in which anthracycline  ...[more]

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