Ontology highlight
ABSTRACT:
SUBMITTER: Monmai C
PROVIDER: S-EPMC6380620 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Monmai Chaiwat C You SangGuan S Park Woo Jung WJ
PloS one 20190219 2
Immune-regulation and homeostasis are critical in cancer therapy and immunomodulatory biomaterials have been used to decrease side effects of immunosuppressant drugs. Anionic macromolecules (CFAMs) were isolated from the seaweed Codium fragile, and its immune-enhancing biological activities were examined in CY-induced immunosuppressed mice. CFAMs improved the splenic lymphocyte proliferation, NK cell activity, and spleen index. The expression of immune-associated genes was highly upregulated in ...[more]