Ontology highlight
ABSTRACT:
SUBMITTER: Yim PD
PROVIDER: S-EPMC6383505 | biostudies-literature | 2019 Jan
REPOSITORIES: biostudies-literature
Yim Peter D PD Gallos George G Perez-Zoghbi Jose F JF Zhang Yi Y Xu Dingbang D Wu Amy A Berkowitz Dan E DE Emala Charles W CW
American journal of physiology. Lung cellular and molecular physiology 20181004 1
Nonvisual opsin (OPN) receptors have recently been implicated in blue light-mediated photorelaxation of smooth muscle in various organs. Since photorelaxation has not yet been demonstrated in airway smooth muscle (ASM) or in human tissues, we questioned whether functional OPN receptors are expressed in mouse and human ASM. mRNA, encoding the OPN 3 receptor, was detected in both human and mouse ASM. To demonstrate the functionality of the OPN receptors, we performed wire myography of ex vivo ASM ...[more]