Ontology highlight
ABSTRACT:
SUBMITTER: Borkar NA
PROVIDER: S-EPMC8183392 | biostudies-literature | 2021 Jul
REPOSITORIES: biostudies-literature
Borkar Niyati A NA Roos Benjamin B Prakash Y S YS Sathish Venkatachalem V Pabelick Christina M CM
Archives of biochemistry and biophysics 20210515
Diseases such as asthma are exacerbated by inflammation, cigarette smoke and even nicotine delivery devices such as e-cigarettes. However, there is currently little information on how nicotine affects airways, particularly in humans, and changes in the context of inflammation or asthma. Here, a longstanding assumption is that airway smooth muscle (ASM) that is key to bronchoconstriction has muscarinic receptors while nicotinic receptors (nAChRs) are only on airway neurons. In this study, we test ...[more]