Ontology highlight
ABSTRACT:
SUBMITTER: Sasaki R
PROVIDER: S-EPMC6384891 | biostudies-literature | 2019 Feb
REPOSITORIES: biostudies-literature
Sasaki Rina R Tainaka Reina R Ando Yuichi Y Hashi Yurika Y Deepak Hadya V HV Suga Yoshiko Y Murai Yuta Y Anetai Masaki M Monde Kenji K Ohta Kiminori K Ito Ikuko I Kikuchi Haruhisa H Oshima Yoshiteru Y Endo Yasuyuki Y Nakao Hitomi H Sakono Masafumi M Uwai Koji K Tokuraku Kiyotaka K
Scientific reports 20190222 1
Protein aggregation is the principal component of numerous protein misfolding pathologies termed proteinopathies, such as Alzheimer's disease, Parkinson's disease, prion disease, and AA amyloidosis with unmet treatment needs. Protein aggregation inhibitors have great potential for the prevention and treatment of proteinopathies. Here we report the development of an automated real-time microliter-scale high throughput screening (MSHTS) system for amyloid aggregation inhibitors using quantum-dot n ...[more]