Ontology highlight
ABSTRACT:
SUBMITTER: Zaitseva J
PROVIDER: S-EPMC6386698 | biostudies-literature | 2019 Feb
REPOSITORIES: biostudies-literature
Zaitseva Jelena J Vaknin Daniel D Krebs Christian C Doroghazi James J Milam Sara L SL Balasubramanian Deepa D Duck Nicholas B NB Freigang Joerg J
Proceedings of the National Academy of Sciences of the United States of America 20190206 8
The crystal structure of the Gram-negative insecticidal protein, GNIP1Aa, has been solved at 2.5-Å resolution. The protein consists of two structurally distinct domains, a MACPF (membrane attack complex/PerForin) and a previously uncharacterized type of domain. GNIP1Aa is unique in being a prokaryotic MACPF member to have both its structure and function identified. It was isolated from a <i>Chromobacterium piscinae</i> strain and is specifically toxic to <i>Diabrotica virgifera virgifera</i> lar ...[more]