Paracetamol versus placebo for knee and hip osteoarthritis.
Ontology highlight
ABSTRACT:
SUBMITTER: Leopoldino AO
PROVIDER: S-EPMC6388567 | biostudies-literature | 2019 Feb
REPOSITORIES: biostudies-literature
Publications
Paracetamol versus placebo for knee and hip osteoarthritis.
Leopoldino Amanda O AO Machado Gustavo C GC Ferreira Paulo H PH Pinheiro Marina B MB Day Richard R McLachlan Andrew J AJ Hunter David J DJ Ferreira Manuela L ML
The Cochrane database of systematic reviews 20190225
<h4>Background</h4>Paracetamol (acetaminophen) is vastly recommended as the first-line analgesic for osteoarthritis of the hip or knee. However, there has been controversy about this recommendation given recent studies have revealed small effects of paracetamol when compared with placebo. Nonetheless, past studies have not systematically reviewed and appraised the literature to investigate the effects of this drug on specific osteoarthritis sites, that is, hip or knee, or on the dose used.<h4>Ob ...[more]
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