Ontology highlight
ABSTRACT:
SUBMITTER: Tochitsky I
PROVIDER: S-EPMC6389275 | biostudies-literature | 2018 Nov
REPOSITORIES: biostudies-literature
Tochitsky Ivan I Kienzler Michael A MA Isacoff Ehud E Kramer Richard H RH
Chemical reviews 20180606 21
Degenerative retinal diseases such as retinitis pigmentosa (RP) and age-related macular degeneration (AMD) affect millions of people around the world and lead to irreversible vision loss if left untreated. A number of therapeutic strategies have been developed over the years to treat these diseases or restore vision to already blind patients. In this Review, we describe the development and translational application of light-sensitive chemical photoswitches to restore visual function to the blind ...[more]