Ontology highlight
ABSTRACT:
SUBMITTER: Vila-Gonzalez M
PROVIDER: S-EPMC6392130 | biostudies-literature | 2019 Feb
REPOSITORIES: biostudies-literature
Vilà-González Marta M Kelaini Sophia S Magee Corey C Caines Rachel R Campbell David D Eleftheriadou Magdalini M Cochrane Amy A Drehmer Daiana D Tsifaki Marianna M O'Neill Karla K Pedrini Edoardo E Yang Chunbo C Medina Reinhold R McDonald Denise D Simpson David D Zampetaki Anna A Zeng Lingfang L Grieve David D Lois Noemi N Stitt Alan W AW Margariti Andriana A
Stem cells (Dayton, Ohio) 20181117 2
The mortality rate for (cardio)-vascular disease is one of the highest in the world, so a healthy functional endothelium is of outmost importance against vascular disease. In this study, human induced pluripotent stem (iPS) cells were reprogrammed from 1 ml blood of healthy donors and subsequently differentiated into endothelial cells (iPS-ECs) with typical EC characteristics. This research combined iPS cell technologies and next-generation sequencing to acquire an insight into the transcription ...[more]