Ontology highlight
ABSTRACT:
SUBMITTER: Dimic DS
PROVIDER: S-EPMC6393868 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Oxidative medicine and cellular longevity 20190213
The newly synthesized coumarin derivative with dopamine, 3-(1-((3,4-dihydroxyphenethyl)amino)ethylidene)-chroman-2,4-dione, was completely structurally characterized by X-ray crystallography. It was shown that several types of hydrogen bonds are present, which additionally stabilize the structure. The compound was tested <i>in vitro</i> against different cell lines, healthy human keratinocyte HaCaT, cervical squamous cell carcinoma SiHa, breast carcinoma MCF7, and hepatocellular carcinoma HepG2. ...[more]