Ontology highlight
ABSTRACT:
SUBMITTER: Maring JA
PROVIDER: S-EPMC6394631 | biostudies-literature | 2019 Feb
REPOSITORIES: biostudies-literature
Journal of cardiovascular translational research 20181119 1
Cell transplantation studies have shown that injection of progenitor cells can improve cardiac function after myocardial infarction (MI). Transplantation of human cardiac progenitor cells (hCPCs) results in an increased ejection fraction, but survival and integration are low. Therefore, paracrine factors including extracellular vesicles (EVs) are likely to contribute to the beneficial effects. We investigated the contribution of EVs by transplanting hCPCs with reduced EV secretion. Interestingly ...[more]