Ontology highlight
ABSTRACT:
SUBMITTER: Dolce LG
PROVIDER: S-EPMC6395372 | biostudies-literature | 2019 Mar
REPOSITORIES: biostudies-literature
Dolce Luciano G LG Silva-Junior Rui M P RMP Assis Leandro H P LHP Nascimento Andrey F Z AFZ Araujo Jackeline S JS Meschede Ingrid P IP Espreafico Enilza M EM de Giuseppe Priscila O PO Murakami Mário T MT
Bioscience reports 20190301 3
Myosin Va (MyoVa) is an actin-based molecular motor that plays key roles in the final stages of secretory pathways, including neurotransmitter release. Several studies have addressed how MyoVa coordinates the trafficking of secretory vesicles, but why this molecular motor is found in exosomes is still unclear. In this work, using a yeast two-hybrid screening system, we identified the direct interaction between the globular tail domain (GTD) of MyoVa and four protein components of exosomes: the W ...[more]