Ontology highlight
ABSTRACT:
SUBMITTER: Cezar TLC
PROVIDER: S-EPMC6395735 | biostudies-literature | 2019 Feb
REPOSITORIES: biostudies-literature
Cezar Talita L C TLC Martinez Renata M RM Rocha Camila da CD Melo Cristina P B CPB Vale David L DL Borghi Sergio M SM Fattori Victor V Vignoli Josiane A JA Camilios-Neto Doumit D Baracat Marcela M MM Georgetti Sandra R SR Verri Waldiceu A WA Casagrande Rubia R
Scientific reports 20190228 1
Acute exposure to UVB irradiation causes skin inflammation and oxidative stress, and long-term exposure to UVB irradiation may lead to carcinogenesis. Our organism has endogenous mechanisms to actively limit inflammation. Maresin 1 (MaR1; 7R,14S-dihydroxy-docosa-4Z,8E,10E,12Z,16Z,19Z-hexaenoic acid) is a pro-resolution lipid mediator derived from the docosahexaenoic acid, which presents anti-inflammatory and pro-resolution effects. However, it remains to be determined if treatment with MaR1 can ...[more]