Ontology highlight
ABSTRACT:
SUBMITTER: Osborne MT
PROVIDER: S-EPMC6398601 | biostudies-literature | 2019 Feb
REPOSITORIES: biostudies-literature
Osborne Michael T MT Ishai Amorina A Hammad Basma B Tung Brian B Wang Ying Y Baruch Amos A Fayad Zahi A ZA Giles Jon T JT Lo Janet J Shin Lisa M LM Grinspoon Steven K SK Koenen Karestan C KC Pitman Roger K RK Tawakol Ahmed A
Psychoneuroendocrinology 20180922
While it is established that psychosocial stress increases the risk of developing diabetes mellitus (DM), two key knowledge gaps remain: 1) the neurobiological mechanisms that are involved in mediating that risk, and 2) the role, if any, that adiposity plays in that mechanism. We tested the hypotheses that: 1) metabolic activity in the amygdala (AmygA), a key center involved in the neurobiological response to stress, associates with subsequent DM risk, and 2) this association is independent of a ...[more]