Ontology highlight
ABSTRACT:
SUBMITTER: Smeets B
PROVIDER: S-EPMC6400824 | biostudies-literature | 2019 Mar
REPOSITORIES: biostudies-literature
Smeets Bart B Cuvelier Maxim M Pešek Jiri J Ramon Herman H
Biophysical journal 20190124 5
We consider a cell as an elastic, contractile shell surrounding a liquid incompressible cytoplasm and with nonspecific adhesion. We perform numerical simulations of this model to study the mechanics of cell-cell separation. By variation of parameters, we are able to recover well-known limits of the Johnson-Kendall-Roberts theory, the Derjaguin-Muller-Toporov model, adhesive vesicles with surface tension (Brochard-Wyart and de Gennes derivation), and thin elastic shells. We further locate biologi ...[more]