Ontology highlight
ABSTRACT:
SUBMITTER: Martikainen M
PROVIDER: S-EPMC6407011 | biostudies-literature | 2019 Feb
REPOSITORIES: biostudies-literature
Glioblastoma (GBM) is the most common type of primary brain tumor in adults. Despite recent advances in cancer therapy, including the breakthrough of immunotherapy, the prognosis of GBM patients remains dismal. One of the new promising ways to therapeutically tackle the immunosuppressive GBM microenvironment is the use of engineered viruses that kill tumor cells via direct oncolysis and via stimulation of antitumor immune responses. In this review, we focus on recently published results of phase ...[more]