Vaccine-based immunotherapy for glioblastoma.
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ABSTRACT:
SUBMITTER: Thomas AA
PROVIDER: S-EPMC6166520 | biostudies-literature | 2013 Jul
REPOSITORIES: biostudies-literature
Publications
Vaccine-based immunotherapy for glioblastoma.
Thomas Alissa A AA Fisher Jan L JL Ernstoff Marc S MS Fadul Camilo E CE
CNS oncology 20130701 4
Glioblastoma remains the most lethal human brain tumor, despite the advent of multimodal treatment approaches. Because immune tolerance plays an important role in tumor progression, adding immunotherapy has become an attractive and innovative treatment approach for these aggressive tumors. Several early-phase clinical trials have demonstrated that vaccine-based immunotherapies, including dendritic cell therapy, peptide-based vaccines and vaccines containing autologous tumor lysates, are feasible ...[more]
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