Ontology highlight
ABSTRACT:
SUBMITTER: Jimenez-Osorio AS
PROVIDER: S-EPMC6410269 | biostudies-literature | 2019 Feb
REPOSITORIES: biostudies-literature
Jiménez-Osorio Angélica Saraí AS Musalem-Younes Claudette C Cárdenas-Hernández Helios H Solares-Tlapechco Jacqueline J Costa-Urrutia Paula P Medina-Contreras Oscar O Granados Julio J López-Saucedo Catalina C Estrada-Garcia Teresa T Rodríguez-Arellano Martha Eunice ME
Medicina (Kaunas, Lithuania) 20190205 2
<i>Background and objectives:</i> Type 2 diabetes (T2D) is a major problem of public health in Mexico. We investigated the influence of five polymorphisms, previously associated with obesity and cardiovascular disease in Europeans and Asians, on T2D in Mexican Mestizos. <i>Materials and Methods:</i> A total of 1358 subjects from 30 to 85 years old were genotyped for five loci: <i>CXCL12</i> rs501120; <i>CDNK2A/B</i> rs1333049; <i>HNF-1α</i> rs2259816; <i>FTO</i> rs9939609; and <i>LEP</i> rs77990 ...[more]