Ontology highlight
ABSTRACT:
SUBMITTER: Ruiz-Rubio L
PROVIDER: S-EPMC6415335 | biostudies-literature | 2018 Feb
REPOSITORIES: biostudies-literature
Polymers 20180211 2
Poly(2-ethyl-2-oxazoline) has become an excellent alternative to the use of poly(ethylene glycol) in pharmaceutical formulations due to its valuable physicochemical and biological properties. This work presents a formulation of poorly-water soluble drug, hydrocortisone, using interpolymer complexes and physical blends of poly(2-ethyl-2-oxazoline)s and two Carbopols<sup>®</sup> (Carbopol 974 and Carbopol 971) for oromucosal administration. The swelling, hydrocortisone release and mucoadhesive pro ...[more]