Ontology highlight
ABSTRACT:
SUBMITTER: Wang L
PROVIDER: S-EPMC6416069 | biostudies-literature | 2019 Mar
REPOSITORIES: biostudies-literature
Phytotherapy research : PTR 20181210 3
Gossypin is a flavone extracted from Hibiscus vitifolius, which has been reported to exhibit anti-inflammatory, antioxidant, and anticancer activities. However, the anticancer properties of gossypin and its molecular mechanism of action against gastric cancer have not been fully investigated. In the present study, we report that gossypin is an Aurora kinase A (AURKA) and RSK2 inhibitor that suppresses gastric cancer growth. Gossypin attenuated anchorage-dependent and anchorage-independent gastri ...[more]