Ontology highlight
ABSTRACT:
SUBMITTER: Longhini ALF
PROVIDER: S-EPMC6417789 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Longhini Ana Leda F ALF Salazar Tatiana E TE Vieira Cristiano C Trinh Thao T Duan Yaqian Y Pay Louise M LM Li Calzi Sergio S Losh Megan M Johnston Nancy A NA Xie Huisheng H Kim Minsu M Hunt Robert J RJ Yoder Mervin C MC Santoro Domenico D McCarrel Taralyn M TM Grant Maria B MB
PloS one 20190314 3
Previously, we showed that mesenchymal stem cells (MSC) can be mobilized into peripheral blood using electroacupuncture (EA) at acupoints, LI-4, LI-11, GV-14, and GV-20. The purpose of this study was to determine whether EA-mobilized MSC could be harvested and expanded in vitro to be used as an autologous cell therapy in horses. Peripheral blood mononuclear cells (PBMC) isolated from young and aged lame horses (n = 29) showed a marked enrichment for MSCs. MSC were expanded in vitro (n = 25) and ...[more]