Ontology highlight
ABSTRACT:
SUBMITTER: Liakouli V
PROVIDER: S-EPMC6418261 | biostudies-literature | 2019 Mar
REPOSITORIES: biostudies-literature
Liakouli Vasiliki V Cipriani Paola P Di Benedetto Paola P Panzera Noemi N Ruscitti Piero P Pantano Ilenia I Berardicurti Onorina O Carubbi Francesco F Esteves Filomena F Mavria Georgia G Del Galdo Francesco F Giacomelli Roberto R
Scientific reports 20190314 1
Systemic sclerosis (SSc) is characterized by microangiopathy with impaired reparative angiogenesis and fibrosis. Epidermal Growth Factor Like-domain 7 (EGFL7), firstly described in endothelial cells plays a pivotal role in angiogenesis. Fibroblasts (FBs) are involved in vascular remodeling, under physiological and pathological conditions. In this study, we investigated: (i) the expression of EGFL7 and its miR-126 in patients affected by diffuse cutaneous SSc (dcSSc); (ii) the ability of Transfor ...[more]