Ontology highlight
ABSTRACT:
SUBMITTER: Morihiro T
PROVIDER: S-EPMC6420501 | biostudies-literature | 2019 Mar
REPOSITORIES: biostudies-literature
Morihiro Toshiaki T Kuroda Shinji S Kanaya Nobuhiko N Kakiuchi Yoshihiko Y Kubota Tetsushi T Aoyama Katsuyuki K Tanaka Takehiro T Kikuchi Satoru S Nagasaka Takeshi T Nishizaki Masahiko M Kagawa Shunsuke S Tazawa Hiroshi H Fujiwara Toshiyoshi T
Scientific reports 20190315 1
While the importance of programmed death-ligand 1 (PD-L1), mutation burden caused by microsatellite instability (MSI), and CD8+ tumor infiltrating lymphocytes (TILs) has become evident, the significance of PD-L1 expression on prognosis still remains controversial. We evaluated the usefulness of combined markers of PD-L1 and MSI or CD8+ TILs as a prognostic biomarker in gastric cancer. A total of 283 patients with gastric cancer were reviewed retrospectively. PD-L1 expression on >5% tumor cells w ...[more]