Ontology highlight
ABSTRACT:
SUBMITTER: Sanz-Navarro M
PROVIDER: S-EPMC6423187 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Sanz-Navarro Maria M Delgado Irene I Torres Miguel M Mustonen Tuija T Michon Frederic F Rice David P DP
Frontiers in physiology 20190312
MEIS1 is a key developmental regulator of several organs and participates in stem cell maintenance in different niches. However, despite the murine continuously growing incisor being a well described model for the study of adult stem cells, <i>Meis1</i> has not been investigated in a dental context. Here, we uncover that <i>Meis1</i> expression in the tooth is confined to the epithelial compartment. Its expression arises during morphogenesis and becomes restricted to the mouse incisor epithelial ...[more]