Ontology highlight
ABSTRACT:
SUBMITTER: Chong HS
PROVIDER: S-EPMC6423956 | biostudies-literature | 2013 Dec
REPOSITORIES: biostudies-literature
Chong Hyun-Soon HS Chen Yunwei Y
Organic letters 20131118 23
Optically active 4-substituted tetrahydroisoquinolines were synthesized via intramolecular Friedel-Crafts (FC) reactions of aziridinium ions in a highly regio- and stereoselective manner. Control experiments suggest the formation and ring-opening of aziridinium ions as the key intermediates in the Lewis acid catalyzed FC reactions. ...[more]