Ontology highlight
ABSTRACT:
SUBMITTER: Fulterer A
PROVIDER: S-EPMC6436828 | biostudies-literature | 2018 May
REPOSITORIES: biostudies-literature
Fulterer Andreas A Andlauer Till F M TFM Ender Anatoli A Maglione Marta M Eyring Katherine K Woitkuhn Jennifer J Lehmann Martin M Matkovic-Rachid Tanja T Geiger Joerg R P JRP Walter Alexander M AM Nagel Katherine I KI Sigrist Stephan J SJ
Cell reports 20180501 5
High-throughput electron microscopy has started to reveal synaptic connectivity maps of single circuits and whole brain regions, for example, in the Drosophila olfactory system. However, efficacy, timing, and frequency tuning of synaptic vesicle release are also highly diversified across brain synapses. These features critically depend on the nanometer-scale coupling distance between voltage-gated Ca<sup>2+</sup> channels (VGCCs) and the synaptic vesicle release machinery. Combining light super ...[more]